Anita CorbettSamuel C. Dobbs Professor of Biology, Senior Associate Dean of Research Emory College, and Co-Director IMSD Program
The Corbett Lab
Lab Location: Rollins 1081DLab Phone: 404-727-4546
Education
- Ph.D. Vanderbilt University (1992)
- B.S. Colgate University (1988)
Research Area
Genetics, Cell, and Developmental Biology
Graduate Program Affiliation
- Biochemistry, Cell & Developmental Biology
- Genetics and Molecular Biology
Research Description
Research in our laboratory primarily focuses on determining the function of evolutionarily-conserved RNA binding proteins. These RNA binding proteins play critical roles at many steps in gene expression. Interestingly, mutations in genes that encode ubiquitously expressed RNA binding proteins often lead to tissue-specific diseases. We study two such RNA binding proteins, one linked to neuronal dysfunction and one associated with a form of muscular dystrophy.
Our approach to science is highly collaborative allowing us to use a large number of experimental approaches and systems to address important biological questions. We use several genetic model systems including the budding yeast, Saccharomyces cerevisiae, the fruit fly, Drosophila, and transgenic mice.
As a complement to genetic approaches, we use biochemistry, cell biology, systems methods (RNA-Seq, proteomics, etc), and structural biology.
Research Lab Description
Research in our laboratory primarily focuses on determining the function of evolutionarily-conserved RNA binding proteins. These RNA binding proteins play critical roles at many steps in gene expression. Interestingly, mutations in genes that encode ubiquitously expressed RNA binding proteins often lead to tissue-specific diseases.